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Model mouse - List of Manufacturers, Suppliers, Companies and Products

Model mouse Product List

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Human-type model animal

Human-type model animal

We will create mice and rats with drug metabolism similar to that of humans!

We have created human-like drug metabolism model mice and rats equipped with artificial chromosome vectors carrying human drug metabolism-related genes. By administering new drugs, we can predict safety for humans, leading to accelerated pharmaceutical development and reduced costs. 【Features】 ■ Improved prediction of safety for humans ■ Accelerated pharmaceutical development and increased success rates ■ Lower costs for new drug development and reduced national healthcare burden *For more details, please refer to the catalog or feel free to contact us.

  • Other experimental equipment

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Ultra First (3 weeks) NASH screening mouse model

Ultra First (3 weeks) NASH screening mouse model

Physiogenex has developed a method for NASH screening that can be implemented in three weeks. The control drugs are ezetimibe and liraglutide.

A test system has been developed by Physiogenex using a unique method (using cyclodextrin, as described later) that allows for the extremely rapid induction of NASH within just three weeks. This model uses 8-week-old male mice and measures parameters such as ALT, AST, liver weight as a percentage of body weight, total cholesterol, triglycerides, and fatty acids, all of which increase within just three weeks (at 11 weeks of age). It also shows an increase in the NAS score (indicators: steatosis, inflammation, fibrosis, ballooning, total score) and significant liver inflammation and fibrosis. Treatment with ezetimibe (5 mg/kg) for two weeks results in a decrease in plasma total cholesterol and liver fat, a reduction in gene expression related to inflammation and fibrosis, and a lower overall NAFLD score due to decreased liver inflammation. Similarly, treatment with liraglutide for two weeks also shows a reduction in body weight and liver weight, as well as a lower overall NAS score due to decreased liver inflammation. For more details, please contact us. *Inquiries can also be made through our website. We will respond promptly. (Search for "Clea Japan" at http://www.clea-japan.com/)

  • Other Contract Life Science Specialization

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"Arthritis model" CIA model CAIA model

"Arthritis model" CIA model CAIA model

Stress-free rearing under advanced microbiological control is essential for the stability of the system. Our company is capable of producing high-quality autoimmune disease models!

We would like to introduce the "Arthritis Model" that we handle. In the production of autoimmune disease models, stress-free breeding under advanced microbiological control is essential for system stability. Furthermore, providing appropriate care for symptoms is also important for maintaining the health of the mice. Our company is capable of producing high-quality autoimmune disease models through advanced breeding management techniques and meticulous attention to the disease state. [Features] ■ Advanced breeding management techniques ■ Meticulous attention to the disease state ■ Capability to produce high-quality autoimmune disease models *For more details, please refer to the PDF materials or feel free to contact us.

  • Animal cells

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